Abstract—Immunodeficiency viruses incur the lack of ability
to fight against pathogens and weaken one’s immune system.
They all belong to a genus lentivirus. Since these viruses do
reverse transcription that lacks normal proofreading of DNA
transcription, they mutates very often. The materials used in
the research include several viruses which could be mutated
from common ancestor; they are SIV, HIV, BIV, and FIV.
Focusing on the four viruses, we conducted two main
experiments using their RNA sequences by munticlass SVM;
for one, analysis of genetic properties by identifying each one’s
structures. For two, comparison of the structural relationship
between a couple of viruses after setting six subsets from four.
In the first one, the structure of all the four immunodeficiency
viruses presented nonlinearity. In the second one, the structural
relationship between SIV and FIV was nonlinear (RBF
function) with extraordinarily high accuracy. While all viruses
showed nonlinear structures, comparison of SIV and FIV
verified us their genetic relationships of nonlinearity. The
genetic similarity of the four viruses supports a notion that they
are rooted from a common ancestor.
Index Terms—Immunodeficiency virus, mutation, structural
relationship, support vector machine (SVM), nonlinear,
common ancestor.
The authors are with the Hankook Academy of Foreign Studies, Republic
of Korea (e-mail:{junyd5469, ojw0414, tonylim0930, choiyewon961001,
p0q1013}@gmail.com, tsyoon@hafs.hs.kr).
[PDF]
Cite:Yoondeok Jeon, Jiwoo Oh, Seungjae Lim, Yewon Choi, Sungmoon Kim, and Taeseon Yoon, "Analysis of Structural Relationship between Immunodeficiency Viruses Using Support Vector Machine," International Journal of Computer Theory and Engineering vol. 7, no. 1, pp. 46-50, 2015.