• Jun 14, 2017 News!Vol.8, No.5 has been indexed by EI (Inspec).   [Click]
  • Nov 09, 2017 News!Vol.9, No.5 has been published with online version. 16 peer reviewed articles from 11 specific areas are published in this issue.   [Click]
  • Jul 19, 2017 News!Vol.9, No.4 has been published with online version. 16 peer reviewed articles from 16 specific areas are published in this issue.   [Click]
General Information
Editor-in-chief
Prof. Wael Badawy
Department of Computing and Information Systems Umm Al Qura University, Canada
I'm happy to take on the position of editor in chief of IJCTE. We encourage authors to submit papers concerning any branch of computer theory and engineering.
IJCTE 2015 Vol.7(1): 46-50 ISSN: 1793-8201
DOI: 10.7763/IJCTE.2015.V7.928

Analysis of Structural Relationship between Immunodeficiency Viruses Using Support Vector Machine

Yoondeok Jeon, Jiwoo Oh, Seungjae Lim, Yewon Choi, Sungmoon Kim, and Taeseon Yoon
Abstract—Immunodeficiency viruses incur the lack of ability to fight against pathogens and weaken one’s immune system. They all belong to a genus lentivirus. Since these viruses do reverse transcription that lacks normal proofreading of DNA transcription, they mutates very often. The materials used in the research include several viruses which could be mutated from common ancestor; they are SIV, HIV, BIV, and FIV. Focusing on the four viruses, we conducted two main experiments using their RNA sequences by munticlass SVM; for one, analysis of genetic properties by identifying each one’s structures. For two, comparison of the structural relationship between a couple of viruses after setting six subsets from four. In the first one, the structure of all the four immunodeficiency viruses presented nonlinearity. In the second one, the structural relationship between SIV and FIV was nonlinear (RBF function) with extraordinarily high accuracy. While all viruses showed nonlinear structures, comparison of SIV and FIV verified us their genetic relationships of nonlinearity. The genetic similarity of the four viruses supports a notion that they are rooted from a common ancestor.

Index Terms—Immunodeficiency virus, mutation, structural relationship, support vector machine (SVM), nonlinear, common ancestor.

The authors are with the Hankook Academy of Foreign Studies, Republic of Korea (e-mail:{junyd5469, ojw0414, tonylim0930, choiyewon961001, p0q1013}@gmail.com, tsyoon@hafs.hs.kr).

[PDF]

Cite:Yoondeok Jeon, Jiwoo Oh, Seungjae Lim, Yewon Choi, Sungmoon Kim, and Taeseon Yoon, "Analysis of Structural Relationship between Immunodeficiency Viruses Using Support Vector Machine," International Journal of Computer Theory and Engineering vol. 7, no. 1, pp. 46-50, 2015.

Copyright © 2008-2015. International Journal of Computer Theory and Engineering. All rights reserved.
E-mail: ijcte@vip.163.com